Senior Principal Scientist / Senior Principal Scientistess / Principal Scientist I / Principal Scientist Iess / Principal Scientist II / Principal Scientist IIess

Job ID

REQ-10079216

Date: Jun 16, 2026

Location: Switzerland

Summary

Job Title: Senior Principal Scientist/Principal Scientist I/II, Oncology (RLT)
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Location: Basel, Switzerland

This role is located in Basel, Switzerland. Please note that Novartis is unable to offer relocation support; apply online using the form below only if you are accessible to this location.

Shape the future of cancer treatment by driving innovative radioligand therapies from discovery to clinic. As a scientific leader within our Oncology Drug Discovery team in Basel, you will lead cutting-edge preclinical research, designing impactful in vivo studies and collaborating across global, multidisciplinary teams to unlock the potential of next-generation cancer treatments. This role offers a unique opportunity to combine scientific excellence with leadership, mentoring talent, influencing strategy, and translating complex data into meaningful insights that accelerate life-changing therapies for patients worldwide.

About the Role

Key Responsibilities

• Design and lead in vivo studies supporting preclinical evaluation of radioligand therapies
• Drive efficacy, biodistribution, imaging, and mechanism of action studies across oncology programs
• Collaborate with cross-functional teams to advance drug candidates toward clinical development
• Manage external partnerships with contract research organizations and academic collaborators
• Mentor, guide, and develop scientists to strengthen scientific and professional capabilities
• Present data and insights clearly to influence decisions across global research and development teams

Essential Requirements

• Doctor of Philosophy in Pharmacology, Cell Biology, or a related biomedical discipline
• Minimum of three years of additional experience in biomedical research within academia or industry
• Strong background in cancer biology with a proven track record of scientific achievement
• Extensive experience designing and managing in vivo oncology studies, including efficacy and pharmacokinetic assessment
• Expertise in ex vivo analysis methods such as flow cytometry, immunofluorescence, immunohistochemistry, or RNA sequencing
• Demonstrated ability to collaborate effectively within multidisciplinary and global research teams
• Excellent communication and presentation skills in English, both written and verbal
• Self-motivated, proactive, and able to independently drive scientific projects forward

Desirable Requirements

• Experience in radioligand therapy development or radiobiology
• Strong understanding of drug development within oncology or related therapeutic areas

This is a dual-level posting. The final level and title for this position will be determined following the completion of the candidate evaluation process, based on skills, experience, and organizational needs.

Why Novartis

Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting, and inspiring each other. Combining to achieve breakthroughs that change patients' lives. Ready to create a brighter future together? Learn more about our culture.

Benefits and Rewards

Learn about all the ways we’ll help you thrive personally and professionally. Read our handbook (PDF 30 MB)

Additional Information

Only applications matching the job profile will be considered.

Apply online using the form below.

Division

Biomedical Research

Business Unit

Research

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No