PhD in Interrogating Chirality at the Nanoscale / PhD in Interrogating Chirality at the Nanoscale

ETH Zurich - September 30, 2025

PhD on Interrogating Chirality at the Nanoscale

100%, Zurich, Fixed-Term

We are seeking a curious and motivated PhD student to join our bionanophotonics team and work at the interface between nanophotonics and digital holography. The aim is to advance the interrogation of chiral systems down to the nanometer scale.

Project Background

Chirality describes whether an object is non-superimposable with its mirror image. Although it is a purely geometric property, chirality plays a crucial role in all living systems, as most biomolecules are chiral, and their interactions with other chiral objects are fundamental to key biological processes. Chiral molecules exist in two forms: a left-handed one and a right-handed one, known as enantiomers. Their handedness significantly influences molecular interactions, often determining the difference between a medical drug and a toxic substance. Consequently, methods for detecting, quantifying, and separating enantiomers are critical across various fields, including biochemistry and pharmaceutics. However, standard methods are often incompatible with heterogeneous and spatially varying chiral samples.

Job Description

This project aims to develop novel methods for studying chirality across different length scales and spectral ranges. The goal is to extract key structural information that transcends mere enantiomer discrimination. You will engage in developing nanophotonic systems that enhance light-chiral matter interactions and novel imaging systems that, when combined, unlock a new understanding of chirality.

Profile

The successful candidate will share our passion for cutting-edge research and bring their motivation and creativity to the team. Clear communication, enjoying collaborative efforts within a respectful team environment, and having basic hands-on lab experience and data analysis skills are essential. Although prior experience in optical imaging, nanofabrication, and data processing is highly valued, it is not mandatory.

Workplace

You will be part of an international and interdisciplinary research group at ETH Zurich, known for pioneering contributions to nanophotonics and its application to the detection of optical chirality. Throughout your PhD, you will encounter a multitude of technologies, including nanofabrication, optics, spectroscopy, data analysis, and numerical simulations.

We Value Diversity

In line with our values, ETH Zurich promotes an inclusive culture. We encourage equality of opportunity, value diversity, and nurture a working and learning environment where the rights and dignity of all staff and students are respected. For further details on our commitment to a fair and open environment, please visit our Equal Opportunities and Diversity website.

Curious? So Are We!

Apply online using the form below. Only applications matching the job profile will be considered.

About ETH Zurich

ETH Zurich is one of the world's leading universities specializing in science and technology. We are renowned for excellent education, cutting-edge fundamental research, and the direct transfer of new knowledge into society. Over 30,000 individuals from more than 120 countries find our university a place that fosters independent thinking and inspires excellence. Located in the heart of Europe while forging connections around the world, we work together to develop solutions for the global challenges of today and tomorrow.

Location : Zürich
Country : Switzerland

Application Form

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